AustralieFrV1, Main, Exploration, bibRecord, 006C34

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3

Identifieur interne : 006C34 ( Main/Exploration ); précédent : 006C33; suivant : 006C35

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3

Auteurs : Meletios Dimopoulos [Grèce] ; Robert Kyle [États-Unis] ; Jean-Paul Fermand [France] ; S. Vincent Rajkumar [États-Unis] ; Jesus San Miguel [Espagne] ; Asher Chanan-Khan [États-Unis] ; Heinz Ludwig [Autriche] ; Douglas Joshua [Australie] ; Jayesh Mehta [États-Unis] ; Morie Gertz [États-Unis] ; Hervé Avet-Loiseau [France] ; Meral Beksac [Turquie] ; Kenneth C. Anderson [États-Unis] ; Philippe Moreau [France] ; Seema Singhal [États-Unis] ; Hartmut Goldschmidt [Allemagne] ; Mario Boccadoro [Italie] ; Shaji Kumar [États-Unis] ; Sergio Giralt [États-Unis] ; Nikhil C. Munshi [États-Unis] ; Sundar Jagannath [États-Unis]

Source :

Blood [ 0006-4971 ] ; 2011.

RBID : Pascal:11-0234147

Descripteurs français

Pascal (Inist)
- Myélome, Consensus, Recommandation, Norme, International, Atelier, Hématologie, Hémopathie maligne lymphoïde, Hémopathie lymphoïde B.
Wicri :
- topic : Recommandation, Norme.

English descriptors

KwdEn :
- B cell neoplasm, Consensus, Hematology, International, Lymphoid neoplasm, Myeloma, Recommendation, Standards, Workshop.

Abstract

A panel of members of the 2009 International Myeloma Workshop developed guidelines for standard investigative workup of patients with suspected multiple myeloma. Both serum and urine should be assessed for monoclonal protein. Measurement of monoclonal protein both by densitometer tracing and/by nephelometric quantitation is recommended, and immunofixation is required for confirmation. The serum-free light chain assay is recommended in all newly diagnosed patients with plasma cell dyscrasias. Bone marrow aspiration and/or biopsy along with demonstration of clonality of plasma cells are necessary. Serum β₂-microglobulin, albumin, and lactate dehydrogenase are necessary for prognostic purposes. Standard metaphase cytogenetics and fluorescent in situ hybridization for 17p, t(4;14), and t(14;16) are recommended. The skeletal survey remains the standard method for imaging screening, but magnetic resonance imaging frequently provides valuable diagnostic and prognostic information. Most of these tests are repeated during follow-up or at relapse.

Affiliations:

Allemagne, Australie, Autriche, Espagne, France, Grèce, Italie, Turquie, États-Unis
Attique (région), Bade-Wurtemberg, District de Karlsruhe, Pays de la Loire, Piémont, Vienne (Autriche), Île-de-France
Athènes, Heidelberg, Nantes, Paris, Turin, Vienne (Autriche)

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 001D63
to stream PascalFrancis, to step Curation: 004178
to stream PascalFrancis, to step Checkpoint: 001C40
to stream Main, to step Merge: 007091
to stream Main, to step Curation: 006C34

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3</title>
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<author><name sortKey="Kyle, Robert" sort="Kyle, Robert" uniqKey="Kyle R" first="Robert" last="Kyle">Robert Kyle</name>
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<author><name sortKey="Chanan Khan, Asher" sort="Chanan Khan, Asher" uniqKey="Chanan Khan A" first="Asher" last="Chanan-Khan">Asher Chanan-Khan</name>
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<author><name sortKey="Joshua, Douglas" sort="Joshua, Douglas" uniqKey="Joshua D" first="Douglas" last="Joshua">Douglas Joshua</name>
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<author><name sortKey="Gertz, Morie" sort="Gertz, Morie" uniqKey="Gertz M" first="Morie" last="Gertz">Morie Gertz</name>
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<author><name sortKey="Avet Loiseau, Herve" sort="Avet Loiseau, Herve" uniqKey="Avet Loiseau H" first="Hervé" last="Avet-Loiseau">Hervé Avet-Loiseau</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Universitaire de Nantes</s1>
<s2>Nantes</s2>
<s3>FRA</s3>
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<placeName><region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
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<author><name sortKey="Beksac, Meral" sort="Beksac, Meral" uniqKey="Beksac M" first="Meral" last="Beksac">Meral Beksac</name>
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<s2>Ankara</s2>
<s3>TUR</s3>
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</inist:fA14>
<country>Turquie</country>
<wicri:noRegion>Ankara University-Ibn Sina Hospital</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C." last="Anderson">Kenneth C. Anderson</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Dana-Farber Cancer Institute</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Dana-Farber Cancer Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Moreau, Philippe" sort="Moreau, Philippe" uniqKey="Moreau P" first="Philippe" last="Moreau">Philippe Moreau</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Universitaire de Nantes</s1>
<s2>Nantes</s2>
<s3>FRA</s3>
<sZ>11 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Singhal, Seema" sort="Singhal, Seema" uniqKey="Singhal S" first="Seema" last="Singhal">Seema Singhal</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Robert H. Lurie Comprehensive Cancer Center</s1>
<s2>Chicago, IL</s2>
<s3>USA</s3>
<sZ>9 aut.</sZ>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Robert H. Lurie Comprehensive Cancer Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Goldschmidt, Hartmut" sort="Goldschmidt, Hartmut" uniqKey="Goldschmidt H" first="Hartmut" last="Goldschmidt">Hartmut Goldschmidt</name>
<affiliation wicri:level="3"><inist:fA14 i1="12"><s1>University of Heidelberg</s1>
<s2>Heidelberg</s2>
<s3>DEU</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boccadoro, Mario" sort="Boccadoro, Mario" uniqKey="Boccadoro M" first="Mario" last="Boccadoro">Mario Boccadoro</name>
<affiliation wicri:level="3"><inist:fA14 i1="13"><s1>University of Torino</s1>
<s2>Torino</s2>
<s3>ITA</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<placeName><settlement type="city">Turin</settlement>
<region type="région" nuts="2">Piémont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kumar, Shaji" sort="Kumar, Shaji" uniqKey="Kumar S" first="Shaji" last="Kumar">Shaji Kumar</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Mayo Clinic</s1>
<s2>Rochester, MN</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>10 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Mayo Clinic</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Giralt, Sergio" sort="Giralt, Sergio" uniqKey="Giralt S" first="Sergio" last="Giralt">Sergio Giralt</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>M. D. Anderson Cancer Center</s1>
<s2>Houston, TX</s2>
<s3>USA</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>M. D. Anderson Cancer Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Munshi, Nikhil C" sort="Munshi, Nikhil C" uniqKey="Munshi N" first="Nikhil C." last="Munshi">Nikhil C. Munshi</name>
<affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Boston Veterans Administration Healthcare System</s1>
<s2>West Roxbury, MA</s2>
<s3>USA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Boston Veterans Administration Healthcare System</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jagannath, Sundar" sort="Jagannath, Sundar" uniqKey="Jagannath S" first="Sundar" last="Jagannath">Sundar Jagannath</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Mt Sinai Medical Center</s1>
<s2>New York, NY</s2>
<s3>USA</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Mt Sinai Medical Center</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Blood</title>
<title level="j" type="abbreviated">Blood</title>
<idno type="ISSN">0006-4971</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Blood</title>
<title level="j" type="abbreviated">Blood</title>
<idno type="ISSN">0006-4971</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>B cell neoplasm</term>
<term>Consensus</term>
<term>Hematology</term>
<term>International</term>
<term>Lymphoid neoplasm</term>
<term>Myeloma</term>
<term>Recommendation</term>
<term>Standards</term>
<term>Workshop</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Myélome</term>
<term>Consensus</term>
<term>Recommandation</term>
<term>Norme</term>
<term>International</term>
<term>Atelier</term>
<term>Hématologie</term>
<term>Hémopathie maligne lymphoïde</term>
<term>Hémopathie lymphoïde B</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Recommandation</term>
<term>Norme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A panel of members of the 2009 International Myeloma Workshop developed guidelines for standard investigative workup of patients with suspected multiple myeloma. Both serum and urine should be assessed for monoclonal protein. Measurement of monoclonal protein both by densitometer tracing and/by nephelometric quantitation is recommended, and immunofixation is required for confirmation. The serum-free light chain assay is recommended in all newly diagnosed patients with plasma cell dyscrasias. Bone marrow aspiration and/or biopsy along with demonstration of clonality of plasma cells are necessary. Serum β<sub>2</sub>
-microglobulin, albumin, and lactate dehydrogenase are necessary for prognostic purposes. Standard metaphase cytogenetics and fluorescent in situ hybridization for 17p, t(4;14), and t(14;16) are recommended. The skeletal survey remains the standard method for imaging screening, but magnetic resonance imaging frequently provides valuable diagnostic and prognostic information. Most of these tests are repeated during follow-up or at relapse.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Autriche</li>
<li>Espagne</li>
<li>France</li>
<li>Grèce</li>
<li>Italie</li>
<li>Turquie</li>
<li>États-Unis</li>
</country>
<region><li>Attique (région)</li>
<li>Bade-Wurtemberg</li>
<li>District de Karlsruhe</li>
<li>Pays de la Loire</li>
<li>Piémont</li>
<li>Vienne (Autriche)</li>
<li>Île-de-France</li>
</region>
<settlement><li>Athènes</li>
<li>Heidelberg</li>
<li>Nantes</li>
<li>Paris</li>
<li>Turin</li>
<li>Vienne (Autriche)</li>
</settlement>
</list>
<tree><country name="Grèce"><region name="Attique (région)"><name sortKey="Dimopoulos, Meletios" sort="Dimopoulos, Meletios" uniqKey="Dimopoulos M" first="Meletios" last="Dimopoulos">Meletios Dimopoulos</name>
</region>
</country>
<country name="États-Unis"><noRegion><name sortKey="Kyle, Robert" sort="Kyle, Robert" uniqKey="Kyle R" first="Robert" last="Kyle">Robert Kyle</name>
</noRegion>
<name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C." last="Anderson">Kenneth C. Anderson</name>
<name sortKey="Chanan Khan, Asher" sort="Chanan Khan, Asher" uniqKey="Chanan Khan A" first="Asher" last="Chanan-Khan">Asher Chanan-Khan</name>
<name sortKey="Gertz, Morie" sort="Gertz, Morie" uniqKey="Gertz M" first="Morie" last="Gertz">Morie Gertz</name>
<name sortKey="Giralt, Sergio" sort="Giralt, Sergio" uniqKey="Giralt S" first="Sergio" last="Giralt">Sergio Giralt</name>
<name sortKey="Jagannath, Sundar" sort="Jagannath, Sundar" uniqKey="Jagannath S" first="Sundar" last="Jagannath">Sundar Jagannath</name>
<name sortKey="Kumar, Shaji" sort="Kumar, Shaji" uniqKey="Kumar S" first="Shaji" last="Kumar">Shaji Kumar</name>
<name sortKey="Mehta, Jayesh" sort="Mehta, Jayesh" uniqKey="Mehta J" first="Jayesh" last="Mehta">Jayesh Mehta</name>
<name sortKey="Munshi, Nikhil C" sort="Munshi, Nikhil C" uniqKey="Munshi N" first="Nikhil C." last="Munshi">Nikhil C. Munshi</name>
<name sortKey="Singhal, Seema" sort="Singhal, Seema" uniqKey="Singhal S" first="Seema" last="Singhal">Seema Singhal</name>
<name sortKey="Vincent Rajkumar, S" sort="Vincent Rajkumar, S" uniqKey="Vincent Rajkumar S" first="S." last="Vincent Rajkumar">S. Vincent Rajkumar</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Fermand, Jean Paul" sort="Fermand, Jean Paul" uniqKey="Fermand J" first="Jean-Paul" last="Fermand">Jean-Paul Fermand</name>
</region>
<name sortKey="Avet Loiseau, Herve" sort="Avet Loiseau, Herve" uniqKey="Avet Loiseau H" first="Hervé" last="Avet-Loiseau">Hervé Avet-Loiseau</name>
<name sortKey="Moreau, Philippe" sort="Moreau, Philippe" uniqKey="Moreau P" first="Philippe" last="Moreau">Philippe Moreau</name>
</country>
<country name="Espagne"><noRegion><name sortKey="San Miguel, Jesus" sort="San Miguel, Jesus" uniqKey="San Miguel J" first="Jesus" last="San Miguel">Jesus San Miguel</name>
</noRegion>
</country>
<country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Ludwig, Heinz" sort="Ludwig, Heinz" uniqKey="Ludwig H" first="Heinz" last="Ludwig">Heinz Ludwig</name>
</region>
</country>
<country name="Australie"><noRegion><name sortKey="Joshua, Douglas" sort="Joshua, Douglas" uniqKey="Joshua D" first="Douglas" last="Joshua">Douglas Joshua</name>
</noRegion>
</country>
<country name="Turquie"><noRegion><name sortKey="Beksac, Meral" sort="Beksac, Meral" uniqKey="Beksac M" first="Meral" last="Beksac">Meral Beksac</name>
</noRegion>
</country>
<country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Goldschmidt, Hartmut" sort="Goldschmidt, Hartmut" uniqKey="Goldschmidt H" first="Hartmut" last="Goldschmidt">Hartmut Goldschmidt</name>
</region>
</country>
<country name="Italie"><region name="Piémont"><name sortKey="Boccadoro, Mario" sort="Boccadoro, Mario" uniqKey="Boccadoro M" first="Mario" last="Boccadoro">Mario Boccadoro</name>
</region>
</country>
</tree>
</affiliations>
</record>

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Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3

Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3

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